Journal: European Heart Journal. Imaging Methods and Practice
Article Title: CT-FFR by expanding coronary tree with Newton–Krylov–Schwarz method to solve the governing equations of CFD
doi: 10.1093/ehjimp/qyae106
Figure Lengend Snippet: Case example. Two patients both with anatomically obstructive stenosis (arrow) on coronary computed tomography angiography (CCTA) ( A and D ). In the first patient ( A–C ), computation of fractional flow reserve from coronary computed tomography angiography (CT-FFR) demonstrates lesion-specific ischaemia of the middle left anterior descending (LAD) stenosis, with a value of 0.74 ( B ). Invasive coronary angiography confirms the functionally obstructive stenosis with an invasive FFR of 0.71 ( C ). In the second patient ( D–F ), CT-FFR predicts no ischaemia of the stenosis in the distal right coronary artery (RCA) with a CT-FFR value of 0.94 ( E ). Invasive FFR of 0.92 similarly demonstrates no ischaemia of RCA.
Article Snippet: To measure FFR, an FFR pressure wire (St Jude Medical, Minneapolis, MN) was positioned distal to the stenosis of interest and hyperaemia was induced by continuous administration of intravenous adenosine (140 mg/kg/min).
Techniques: Computed Tomography